Staphylococcus aureus virulence factors and disease
نویسندگان
چکیده
The genus Staphylococcus is composed of Gram-positive bacteria with diameters of 0.5-1.5 μm, characterized by individual cocci that divide in more than one plane to form grape-like clusters [1]. These bacteria are non-motile, nonspore forming facultative anaerobes, featuring a complex nutritional requirement for growth [2-4], a low G+C content of DNA (in the range of 30-40 mol%) [5], a tolerance to high concentrations of salt [2] and resistance to heat [6]. The genus Staphylococcus is traditionally divided in two groups based on the bacteria ability to produce coagulase, an enzyme that causes blood clotting: the coagulase-positive staphylococci, which includes the most known species Staphylococcus aureus; and the coagulase-negative staphylococci (CoNS), which are common commensals of the skin [5,7].
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